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The Women’s AntioxidantCardiovascular Study (n = 2824), a trial of vitamin E, betacarotene, and vitamin C, for the secondary prevention ofcardiovascular disease reported no slowing of cognitivechange among women with pre-existing cardiovasculardisease or cardiovascular disease risk factors (Kang et al.,2009). These FOXO3 proteins have the ability to activate the genetic expression all ofCDKIs mentioned above (Hendrick 2012).

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The latter policyshift we address in this chapter seems to be making a virtue out of necessity.

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Chondroitin was also found to cause a significant improvementin pain and mobility.

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